The first thing is that each comp (in the current meta) MUST have 1 of each of these things
A Duelist
A initator
A smoke
Cypher/KJ or Viper (on bind/split)
If a comp does not have one of these it suffers greatly. The fifth spot is dependent on map and in current meta it is either a second smoke or second initator. To run vyse would be to choose her as the 5th and she is one of the worst in this case.
Agents as a better 5th then here in no order:
Jett/Raze/Phoniex (with new buffs)/Neon/Yoru/Sova/Fade/Breach/Gekko/Kayo/Skye/Harbor/Viper/Omen/Astra/Brim/Cypher/KJ/Deadlock
Debatable (but still better imo):
Iso/Clove/Chamber/Sage
Not better:
Reyna
So I dont get why teams would every play her when theres so many better options? Can someone explain how/why she is better than the agents I listed in any gven comp as a 5th?