Right now we have:
Americas - 3 sub regions each have 2 teams qualify
EMEA - Multiple sub regions have 1 team qualify each, the 2nd place teams play for an additional slot in playoffs
APAC - 1 team from each sub region, single elim in playoffs (this is crazy)
I think I like the way EMEA does it the most, giving the 2nd seed something to play for but not outright rewarding it like Americas.