THIS IS ALL HYPOTHETICAL BTW
if groups are made by drawing from 4 pools, here's an idea of what the groups could look like
i think it's possible that as the Berlin winner, Gambit could be considered "EMEA #1" and as a result, Acend and Fnatic could be considered EMEA #2 and #3, respectively, which is why I have Acend in Pool B despite being the "#1" seed from EMEA
Pool A (#1 seed from regions that have 2 slots, minus EMEA since the Berlin winner is from EMEA):
Berlin Winner (Gambit Esports)
NA #1 (Sentinels)
BR #1 (Team Vikings)
SEA #1 (X10 Esports)
Pool B (#1 seed from regions that have 1 slot, plus EMEA #1 since they were excluded from Pool A):
EMEA #1 (Acend)
KR #1 (Vision Strikers)
JP #1 (Crazy Raccoon)
LATAM #1 (KRÜ Esports)
Pool C (remaining #2 seeds):
EMEA #2 (Fnatic)
NA #2 (Envy)
BR #2 (Keyd Stars)
SEA #2 (Team Secret)
Pool D (LCQ Winners):
EMEA LCQ (Team Liquid)
NA LCQ (Cloud9 Blue)
SA LCQ (FURIA)
APAC LCQ (FULL SENSE)
each group would consist of 1 team from each pool, with no group consisting of more than one team per region
here's an idea of potential groups:
Group A:
Berlin Winner (Gambit Esports)
LATAM #1 (KRÜ Esports)
NA #2 (Envy)
APAC LCQ (FULL SENSE)
Group B:
NA #1 (Sentinels)
JP #1 (Crazy Raccoon)
EMEA #2 (Fnatic)
SA LCQ (FURIA)
Group C:
BR #1 (Team Vikings)
EMEA #1 (Acend)
SEA #2 (Team Secret)
NA LCQ (Cloud9 Blue)
Group D:
SEA #1 (X10 Esports)
KR #1 (Vision Strikers)
BR #2 (Keyd Stars)
EMEA LCQ (Team Liquid)
Edit: some clarification about why I pushed down EMEA #1 to Pool B despite being a top region: I'm not trying to "punish" Acend for EMEA winning Berlin; my reasoning is that if Gambit HADN'T won, they would have been EMEA #1 and Acend would have been EMEA #2. as a result, since EMEA earned an "extra" slot from Berlin, I'm considering Gambit as EMEA #1, Acend as EMEA #2, and Fnatic as EMEA #3, and seeded them accordingly (Gambit in Pool A, Acend in Pool B, Fnatic in Pool C). I also do agree that KR is stronger than BR and SEA, but since BR and SEA have 2 seeds while KR only has 1, I think it's likely that KR will be put in the same pool as other regions with only 1 seed (LATAM and JP), while BR #1 and SEA #1 will be put in Pool A since they are from regions with 2 seeds.
I personally think that Riot will wait until VCT 2021 is over to factor regional performance into their decision-making for future international events, and I very well could be wrong, but we'll see what happens!
I want to emphasize that this seeding is not based on the strength of individual teams, but rather just based on regional allocations of slots; for example, if I did it based on past performance, I would have Pool A consist of Gambit, Sentinels, Acend, and Envy (Envy getting a higher pool placement due to strong performance at Berlin)