If we think about it tho 100t will be going against Lev, Loud(With a subbed less), EG(idk jawg could do sumn, but im taking 100t), mibr + fur(:skull, but maybe xand and pancada save furia who knows), and that leaves them with a min record of 3-7 max record of 8-2.
Sentinels goes against Kru(i think kru have been kind of exposed these last few series and is a very doable matchup), Sen v C9(yeah c9 can always have Oxy9 go crazy, so idk), G2(look good, but also dependent on icy going crazy(while valyn does do great, i think icy really needs to perform to consistently look great on their attack halves), NRG(truly mid after what we have seen), So min record of 3-7 or 7-3.
Now, I think why 100t looks so good is because of their strats and some individual talents. Whether its cryo popping off, asuna or bang. They all seem to have great talent. On top of that, their best map bind seems some what unpenetrable when it comes to their defensive half. But it has shown holes.
TLDR: Sen has a chance, but its reliant on relying on new comps, strats, and better anti-strating coming into this part of the season. Its unfortunate only G2 is coming from this side of the bracket, but sen has a chance depending on how they develop.
A suggestion I think might be useful is starting to use double duelist or 0 duelist comps on some maps. The main reasoning why TenZ was taken off that duelist position was because of his decision making was too rash and he was pressured to be primary entry. With his time as flex and now, zekken flourishing, tenz could take that jett or yoru spot on some maps, allowing zekken to do what he does best on raze. Also, zekken started his career as an igl and flex player. We have seen many comps in other regions with no duelists, zekken has experience playing agents such as sova and others. We could definitely see some interesting plays come out of sen, since their roster is really flexible when there is more though to it. Will see how life pans out though.