I think Gambit would do fine still. I think they kind of fell off because everyone watched and learned how they played. Like nAts changed the way sentinels were seen/played etc. Their players of Redgar, Chronicle, nAts and Sheydos are still relevant and up to par individually d3ffo is bit hit or miss, but I actually think he would still be good enough for current meta. Also especially nAts looked more comfortable on M3C who still were top 5 EMEA team for most of last year. And Gambit were playing Reyna on Haven because it was their perma ban.
Ofc it hard to say because teams would adapt mid game and not just follow their 1.5 year old gameplan. If they were just same everything 2021 Gambit then they would struggle, but as I said their individuals as well as adaptation would win them games I think because as I said this same roster could still be playing on top level.