(if you have them obviously)
I use the front one for my main (E) ability, and I use the back one for in game comms
(1 exception with raze, I use the satchels, and I set the nade to Q)
DBStudios [#2]Wait dude you are so fucking smart I never thought about using the mouse bottoms for game comms omg. Also I use them for like secondary util like raze blast packs and stuff makes it easier to use.
yh the reason I did it is because I play a lot of Jett, and on my old mouse I had a third button behind the scroll wheel for the smokes, and the updraft wasn't worth a mouse button, so the next most useful thing was comms