You sign all 5 players of Fnatic under an NA org and they'll win.
I don't think this Champions has proven any region (other than China) is a standout major region.
Teams like Liquid and Navi have the highest highs but their lows are placing 16th worthy.
Same can be said for many other teams.
So far, only Fnatic and I'd say PRX have shown consistency with their results, else it's anyone's game based on who's feeling it more.
That being said, CIS aimers own FPS gaming. China is coming close second and that's insane to see a region grow like that!